Altered Carbohydrate Composition of Salivary Mucins from Patients with Cystic Fibrosis and the Adhesion of Pseudomonas aeruginosa

Abstract excerpt

We compared the chemical composition of salivary mucin glycopeptides from cystic fibrosis (CF) and from non-CF subjects and the adhesion of Pseudomonas aeruginosa to these different salivary glycopeptides. Three pools of CF saliva, four pools of non-CF saliva, one individual CF saliva, and one individual non-CF saliva were studied. The soluble fraction of the saliva was treated with pronase, and gel filtration...

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