KNQ1, a Kluyveromyces lactis gene encoding a drug efflux permease.

doi:10.1007/s00294-003-0449-5

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Article

KNQ1, a Kluyveromyces lactis gene encoding a drug efflux permease.

Current genetics - 1 Feb 2004

Takacova Maria, Imrichova Denisa, Cernicka Jana, Gbelska Yvetta, Subik Julius

Abstract excerpt

Several transport systems play an important role in conferring multiple drug resistance, presumably due to their catalysis of the energy-dependent extrusion of a large number of structurally and functionally unrelated compounds out of the cells. In the present work, the gene named KNQ1 (encoding Kluyveromyces lactis membrane permease) was cloned by functional complementation of the cycloheximide-hypersensitivity...

Topics

Chromosomes, Fungal
Cloning, Molecular
Drug Resistance, Fungal
Drug Resistance, Multiple
Gene Deletion
Genes, Fungal
Genetic Complementation Test
Kluyveromyces
Membrane Transport Proteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxidative Stress

Phenotype

Phylogeny

Physical Chromosome Mapping

RNA, Messenger

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

Open in PubMed

Identifiers

PMID: 14595517
DOI: 10.1007/s00294-003-0449-5

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