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Article

Fungal ATP-binding cassette (ABC) transporters in drug resistance & detoxification.

Current drug targets - 1 Apr 2006

Sipos György, Kuchler Karl

Abstract excerpt

Pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi. PDR shares several similarities with processes in bacteria and higher eukaryotes. In mammalian cells, multidrug resistance (MDR) develops from an initial single drug resistance, eventually leading to a broad cross-resistance to many structurally and functionally unrelated compounds. Notably, a number of membrane-embedded...

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PMID: 16611035
DOI: 10.2174/138945006776359403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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