Article
Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations.
BMC evolutionary biology - 27 Feb 2012
Chen Bing, Wagner Andreas
Abstract excerpt
BACKGROUND: In the laboratory, the Drosophila melanogaster heat shock protein Hsp90 can buffer the phenotypic effects of genetic variation. Laboratory experiments either manipulate Hsp90 activity pharmacologically, or they induce mutations with strong effects in the gene Hsp83, the single-copy fly gene encoding Hsp90. It is unknown whether observations from such laboratory experiments are relevant in the wild....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.