Article
HSP90 affects the expression of genetic variation and developmental stability in quantitative traits.
Proceedings of the National Academy of Sciences of the United States of America - 26 Feb 2008
Sangster Todd A, Salathia Neeraj, Undurraga Soledad, Milo Ron, Schellenberg Kurt, Lindquist Susan, Queitsch Christine
Abstract excerpt
Modulation of the activity of the molecular chaperone HSP90 has been extensively discussed as a means to alter phenotype in many traits and organisms. Such changes can be due to the exposure of cryptic genetic variation, which in some instances may also be accomplished by mild environmental alteration. Should such polymorphisms be widespread, natural selection may be more effective at producing phenotypic change...
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