Effects of small Hsp genes on developmental stability and microenvironmental canalization.

doi:10.1186/1471-2148-10-284

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Article

Effects of small Hsp genes on developmental stability and microenvironmental canalization.

BMC evolutionary biology - 16 Sept 2010

Takahashi Kazuo H, Rako Lea, Takano-Shimizu Toshiyuki, Hoffmann Ary A, Lee Siu F

Abstract excerpt

BACKGROUND: Progression of development has to be insulated from the damaging impacts of environmental and genetic perturbations to produce highly predictable phenotypes. Molecular chaperones, such as the heat shock proteins (HSPs), are known to buffer various environmental stresses, and are deeply involved in protein homeostasis. These characteristics of HSPs imply that they might affect developmental buffering...

Topics

Animals
Drosophila Proteins
Drosophila melanogaster
Heat-Shock Proteins
Male
Phenotype
Polymerase Chain Reaction
RNA Interference
Wings, Animal

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Identifiers

PMID: 20846409
DOI: 10.1186/1471-2148-10-284
PMCID: PMC2949873

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