Article
Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants.
Proceedings of the National Academy of Sciences of the United States of America - 11 Nov 2003
d Graaff Wim, Tomotsune Daihachiro, Oosterveen Tony, Takihara Yoshihiro, Koseki Haruhiko, Deschamps Jacqueline
Abstract excerpt
Polycomb-group (Pc-G) proteins ensure late maintenance of transcriptional repression outside the expression domain of target genes in flies and vertebrates. They act in complexes, presumably by modulating chromatin structure. In Drosophila, they have been found to be associated with transcription...
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