Article
Direct interaction of the Polycomb protein with Antennapedia regulatory sequences in polytene chromosomes of Drosophila melanogaster.
The EMBO journal - 1 Jan 1991
Zink B, Engström Y, Gehring W J, Paro R
Abstract excerpt
The Polycomb (Pc) gene is responsible for the elaboration and maintenance of the expression pattern of the homeotic genes during development of Drosophila. In mutant Pc- embryos, homeotic transcripts are ectopically expressed, leading to abdominal transformations in all segments. From this it was...
Topics
- Animals
- Chromosome Mapping
- Drosophila Proteins
- Drosophila melanogaster
- Exons
- Genes, Homeobox
- Homozygote
- Mutation
- Polycomb Repressive Complex 1
- Promoter Regions, Genetic
- Protein Binding
- Proteins
- Recombinant Fusion Proteins
- Regulatory Sequences, Nucleic Acid
- beta-Galactosidase