Article
Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activity.
Journal of bacteriology - 1 Nov 2003
Hesse Lars, Bostock Julieanne, Dementin Sebastien, Blanot Didier, Mengin-Lecreulx Dominique, Chopra Ian
Abstract excerpt
Chlamydiae are unusual obligate intracellular bacteria that cause serious infections in humans. Chlamydiae contain genes that appear to encode products with peptidoglycan biosynthetic activity. The organisms are also susceptible to antibiotics that inhibit peptidoglycan synthesis. However, chlamydiae do not synthesize detectable peptidoglycan. The paradox created by these observations is known as the chlamydial...
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