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Article

Isolation and characterization of a Chlamydia muridarum tc0237 mutant from a genetic screen that is attenuated in epithelial cells.

PloS one - 1 Jan 2025

Jacobs Kaylee R, Ardizzone Caleb M, Banerjee Arkaprabha, Toh Evelyn, Zhang Xiaoli, Nelson David E

Abstract excerpt

Chlamydia are obligate intracellular bacterial pathogens that infect a wide range of vertebrate hosts. Despite having highly conserved genomes, closely related Chlamydia species can exhibit distinct host and tissue tropisms. The host tropisms of the human pathogen Chlamydia trachomatis and the closely related mouse pathogen Chlamydia muridarum are influenced by their ability to evade host immune responses,...

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Identifiers

PMID: 40763156
DOI: 10.1371/journal.pone.0329637
PMCID: PMC12324114

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