Article
Molecular pathogenesis of nephrogenic diabetes insipidus.
Clinical and experimental nephrology - 1 Mar 2003
Nguyen Minhtri K, Nielsen Søren, Kurtz Ira
Abstract excerpt
There have been significant advances recently in the understanding of the molecular causes of nephrogenic diabetes insipidus. The resistance of the collecting duct to the action of vasopressin in this disorder results from abnormalities in several of the intricate steps that mediate the increase in principal cell hydraulic conductivity in response to the hormone. In this article, we review the current...
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