Article
Vasopressin type-2 receptor and aquaporin-2 water channel mutants in nephrogenic diabetes insipidus.
The American journal of the medical sciences - 1 Nov 1998
Deen P M, Knoers N V
Abstract excerpt
The regulation of water excretion by the kidney is one of the few physiologic processes that are prominent in everyday life. This process predominantly occurs in renal collecting duct cells, where transcellular water reabsorption is induced after binding of the pituitary hormone arginine-vasopressin to its vasopressin type-2 receptor and the subsequent insertion of aquaporin-2 (AQP2) water channels in the apical...
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