Article
Aquaporin-2 water channel mutations causing nephrogenic diabetes insipidus.
Proceedings of the Association of American Physicians - 1 Jan 2000
van Os C H, Deen P M
Abstract excerpt
Since the discovery of aquaporin water channels, insight into the molecular mechanism by which rapid osmotic water occurs across cell membranes has greatly improved. Aquaporin-2 is the vasopressin-responsive water channel in the collecting duct, and vasopressin control of water permeability in the collecting duct occurs in two ways: a short-term regulation and a long-term adaptation. In congenital nephrogenic...
Topics
- Animals
- Aquaporin 2
- Aquaporin 6
- Aquaporins
- Diabetes Insipidus, Nephrogenic
- Genes, Dominant
- Genes, Recessive
- Humans
- Kidney Tubules, Collecting
- Mutation