Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aquaporin 2 mutations in nephrogenic diabetes insipidus.

Seminars in nephrology - 1 May 2008

Loonen Anne J M, Knoers Nine V A M, van Os Carel H, Deen Peter M T

Abstract excerpt

Water reabsorption in the renal collecting duct is regulated by the antidiuretic hormone vasopressin (AVP). When the vasopressin V2 receptor, present on the basolateral site of the renal principal cell, becomes activated by AVP, aquaporin-2 (AQP2) water channels will be inserted in the apical membrane, and in this fashion, water can be reabsorbed from the pro-urine into the interstitium. The essential role of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aquaporin 2
Share to Diabetes Insipidus, Nephrogenic
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to AQP2 gene

Share to Genes, Dominant

Share to Genes, Recessive

Share to Mutation

Source

Identifiers

PMID: 18519086
DOI: 10.1016/j.semnephrol.2008.03.006

Genes

AQP2
AVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aquaporin 2 mutations in nephrogenic diabetes insipidus.PMID 18519086Read ↗

Aquaporin-2 water channel mutations causing nephrogenic diabetes insipidus.Semantic proximity Read ↗

Vasopressin type-2 receptor and aquaporin-2 water channel mutants in nephrogenic diabetes insipidus.Semantic proximity Read ↗

Genetic basis of nephrogenic diabetes insipidus.Semantic proximity Read ↗

V2R mutations and nephrogenic diabetes insipidus.Semantic proximity Read ↗

Vasopressin receptor mutations causing nephrogenic diabetes insipidus.Semantic proximity Read ↗

Diabetes insipidus.Semantic proximity Read ↗

Nephrogenic diabetes insipidus.Semantic proximity Read ↗

[Vasopressin type 2 receptor mutations in congenital diabetes insipidus].Semantic proximity Read ↗

Hereditary Nephrogenic Diabetes Insipidus: Pathophysiology and Possible Treatment. An Update.Semantic proximity Read ↗

Routing of the aquaporin-2 water channel in health and disease.Semantic proximity Read ↗

Aquaporin 2: from its discovery to molecular structure and medical implications.Semantic proximity Read ↗

A Novel Mutation in the AVPR2 Gene Causing Congenital Nephrogenic Diabetes InsipidusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.