Article
Changes of percentages in immune cells phenotypes and cytokines production during two-year IFN-beta-1a treatment in multiple sclerosis patients.
Journal of neurology - 1 Oct 2003
Mirowska Dagmara, Skierski Janusz, Paź Aleksandra, Koronkiewicz Mirosława, Zaborski Jacek, Kruszewska Jadwiga, Członkowski Andrzej, Członkowska Anna
Abstract excerpt
OBJECTIVE: The aim of the study was to find out whether INF-beta-1a influences the immune profile of peripheral blood (PB) leukocytes in MS patients. METHOD: We have studied 20 patients with relapsing-remitting form of MS treated with INF-beta-1a using twocolor cytometry. We determined immune cells phenotypes and production of some cytokines: IL-4, IL-10, IL-12, IFN-gamma, before drug administration and after...
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