Article

Interferon-beta changes the expression of IL10, IL23A and FOXP3 on Multiple Sclerosis patients' T cells

2021-01-16

Abstract excerpt

<h4>Aim: </h4> of the Study: Multiple sclerosis (MS) is an autoimmune disorder causing demyelination in axons. Available therapies target different molecules, but not all have therapeutic effects on disease progression, and this effect can only be seen after a long-time administration. Interferon beta (IFN-β), an MS therapy for many years, slows down the disease progression and reduces disease symptoms by targetin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d0917a89-ec04-58a5-a34c-a5fd2ab93340
DOI: 10.22541/au.161078363.36073773/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Interferon-beta changes the expression of IL10, IL23A and FOXP3 on Multiple Sclerosis patients' T cellsDOI 10.22541/au.161078363.36073773/v1Read

The regulatory mechanism and potential application of IL-23 in autoimmune diseasesSemantic proximity Read

TGF-β Isoforms and Receptors: A Gene Expression Analysis in Multiple Sclerosis Patients and Normal IndividualsSemantic proximity Read

Changes of percentages in immune cells phenotypes and cytokines production during two-year IFN-beta-1a treatment in multiple sclerosis patients.Semantic proximity Read

Th17 Cell, the New Player of Neuroinflammatory Process in Multiple SclerosisSemantic proximity Read

GEO Data Sets Analysis On Mechanism of Action of IFNβ-1a Treatment in Multiple SclerosisSemantic proximity Read

Cytokine networks in multiple sclerosis: lost in translationSemantic proximity Read

Roles of T helper 17 cells and interleukin‐17 in neuroautoimmune diseases with emphasis on multiple sclerosis and Guillain‐Barré syndrome as well as their animal modelsSemantic proximity Read

Which immune cells matter? The immunopathogenesis of multiple sclerosis.Semantic proximity Read

CD8<sup>+</sup>T cells in multiple sclerosisSemantic proximity Read

Complex immunomodulatory effects of interferon‐β in multiple sclerosis include the upregulation of T helper 1‐associated marker genesSemantic proximity Read

Interferon-beta therapy in multiple sclerosis: the short-term and long-term effects on the patients’ individual gene expression in peripheral bloodSemantic proximity Read

miRNA-485 Regulates Th17 Generation and Pathogenesis in Experimental Autoimmune Encephalomyelitis through Targeting STAT3Semantic proximity Read