Article
Cytokine flow cytometry differentiates the clinical status of multiple sclerosis (MS) patients.
Clinical and experimental immunology - 1 Mar 1999
Inogés S, Merino J, Bandrés E, De Castro P, Subirá M L, Sánchez-Ibarrola A
Abstract excerpt
In this study we have examined intracellular cytokines in peripheral blood mononuclear cells (PBMC) of MS patients by flow cytometry (cytokine flow cytometry). MS progressive patients showed an increased number of cells producing interferon-gamma (IFN-gamma) after activation with phorbol 12-myristate 13-acetate and ionomycin, compared with patients with clinically inactive forms (P < 0001) and with healthy...
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