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Article

Altered phenotype and function of blood dendritic cells in multiple sclerosis are modulated by IFN-beta and IL-10.

Clinical and experimental immunology - 1 May 2001

Huang Y M, Stoyanova N, Jin Y P, Teleshova N, Hussien Y, Xiao B G, Fredrikson S, Link H

Abstract excerpt

Multiple sclerosis (MS) is assumed to result from autoaggressive T cell-mediated immune responses, in which T helper type 1 (Th1) cells producing cytokines, e.g. IFN-gamma and lymphotoxin promote damage of oligodendrocyte-myelin units. Dendritic cells (DCs) as potent antigen presenting cells initiate and orchestrate immune responses. Whether phenotype and function of DCs with respect to Th1 cell promotion are...

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Identifiers

PMID: 11422209
DOI: 10.1046/j.1365-2249.2001.01504.x
PMCID: PMC1906056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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