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Article

Altered Immune Phenotypes and HLA-DQB1 Gene Variation in Multiple Sclerosis Patients Failing Interferon β Treatment.

Frontiers in immunology - 1 Jan 2021

Devi-Marulkar Priyanka, Moraes-Cabe Carolina, Campagne Pascal, Corre Béatrice, Meghraoui-Kheddar Aida, Bondet Vincent, Llibre Alba, Duffy Darragh, Maillart Elisabeth, Papeix Caroline, Pellegrini Sandra, Michel Frédérique

Abstract excerpt

Background: Interferon beta (IFNβ) has been prescribed as a first-line disease-modifying therapy for relapsing-remitting multiple sclerosis (RRMS) for nearly three decades. However, there is still a lack of treatment response markers that correlate with the clinical outcome of patients. Aim: To determine a combination of cellular and molecular blood signatures associated with the efficacy of IFNβ treatment using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34113337
DOI: 10.3389/fimmu.2021.628375
PMCID: PMC8185344

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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