Article

IFNβ-1b treatment leads to changes in the B cell subset and cytokine secretion profile in patients with relapsing-remitting multiple sclerosis

2022-02-26

Abstract excerpt

In order to explore the effect of IFNβ-1b treatment on B cell phenotype and function in RRMS patients, blood was drawn from RRMS patients before treatment and again 2 and 6 months after every other day injections of IFNβ-1b. Cryopreserved peripheral blood mononuclear cells (PBMCs) were thawed and stained with panels of antibodies against B cell surface antigens and the intracellular cytokines, IL-10 and IL-6. At b...

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Literature Corpus work: a4eb6034-4516-583b-b890-98a162c51cae
DOI: 10.1101/2022.02.25.22270266

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