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Article

Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Nov 2003

Guillet Marie, Boiteux Serge

Abstract excerpt

Abasic (AP) sites are among the most frequent endogenous lesions in DNA and present a strong block to replication. In Saccharomyces cerevisiae, an apn1 apn2 rad1 triple mutant is inviable because of its incapacity to repair AP sites and related 3'-blocked single-strand breaks (M. Guillet and S. Boiteux, EMBO J. 21:2833, 2002). Here, we investigated the origin of endogenous AP sites in yeast. Our results show that...

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Identifiers

PMID: 14585995
DOI: 10.1128/MCB.23.22.8386-8394.2003
PMCID: PMC262356

Genes

OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae.PMID 14585995Read ↗

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