Article
Emergence of a fluoroquinolone-resistant strain of Streptococcus pneumoniae in England.
The Journal of antimicrobial chemotherapy - 1 Dec 2003
Johnson A P, Sheppard C L, Harnett S J, Birtles A, Harrison T G, Brenwald N P, Gill M J, Walker R A, Livermore D M, George R C
Abstract excerpt
OBJECTIVE: To determine the epidemiological relationship between pneumococci of serotype 9V, with reduced susceptibility to ciprofloxacin, penicillin and erythromycin, referred to the Reference Laboratory during 1997-2001. METHODS: Isolates were characterized by multilocus sequence typing (MLST), PFGE, and sequencing of parC and gyrA. Relevant clinical data were sought. RESULTS: Forty-eight isolates were received...
Topics
- Aged
- Aged, 80 and over
- Anti-Bacterial Agents
- DNA Gyrase
- DNA Topoisomerase IV
- Drug Resistance, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- England
- Female
- Fluoroquinolones