Increase in fluoroquinolone non-susceptibility among clinical Streptococcus pyogenes in Belgium during 2007-10.

doi:10.1093/jac/dks281

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Article

Increase in fluoroquinolone non-susceptibility among clinical Streptococcus pyogenes in Belgium during 2007-10.

The Journal of antimicrobial chemotherapy - 1 Nov 2012

Van Heirstraeten Liesbet, Leten Gert, Lammens Christine, Goossens Herman, Malhotra-Kumar Surbhi

Abstract excerpt

OBJECTIVES: To study the temporal evolution of fluoroquinolone non-susceptibility among Streptococcus pyogenes during 2007-10 in Belgium. METHODS: S. pyogenes (n = 4690) recovered from patients with tonsillopharyngitis or skin, wound or invasive infections were screened for fluoroquinolone non-susceptibility. A selection of fluoroquinolone-non-susceptible strains was investigated for resistance mechanisms:...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents
Antigens, Bacterial
Bacterial Outer Membrane Proteins
Belgium
Carrier Proteins
Child
Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA Gyrase

DNA Topoisomerase IV

DNA, Bacterial

Drug Resistance, Bacterial

Female

Fluoroquinolones

Genotype

Source

Open in PubMed

Identifiers

PMID: 22815354
DOI: 10.1093/jac/dks281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-22815354-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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