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Article

Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005.

Antimicrobial agents and chemotherapy - 1 Jan 2007

Adam Heather J, Schurek Kristen N, Nichol Kimberly A, Hoban Chris J, Baudry Trish J, Laing Nancy M, Hoban Daryl J, Zhanel George G

Abstract excerpt

Molecular characterization of fluoroquinolone-resistant Streptococcus pneumoniae in Canada was conducted from 1997 to 2005. Over the course of the study, 205 ciprofloxacin-resistant isolates were evaluated for ParC and GyrA quinolone resistance-determining region (QRDR) substitutions, substitutions in the full genes of ParC, ParE, and GyrA, reserpine sensitivity, and serotype and by pulsed-field gel...

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Identifiers

PMID: 17088485
DOI: 10.1128/AAC.00609-06
PMCID: PMC1797689

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