Article
Worldwide incidence, molecular epidemiology and mutations implicated in fluoroquinolone-resistant Streptococcus pneumoniae: data from the global PROTEKT surveillance programme.
The Journal of antimicrobial chemotherapy - 1 Dec 2003
Canton R, Morosini M, Enright M C, Morrissey I
Abstract excerpt
OBJECTIVES: To analyse the mutations and epidemiology associated with fluoroquinolone-resistant pneumococci collected as part of the PROTEKT global surveillance programme during 1999-2000. METHODS: Sixty-nine centres in 25 countries submitted a total of 3362 Streptococcus pneumoniae isolates, for which the MICs of antimicrobial agents were determined using NCCLS methodology. RESULTS: Levofloxacin resistance was...
Topics
- Amino Acid Substitution
- Anti-Bacterial Agents
- DNA Gyrase
- DNA Topoisomerase IV
- Drug Resistance, Bacterial
- Fluoroquinolones
- Humans
- Microbial Sensitivity Tests
- Molecular Epidemiology
- Mutation