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Article

Changes in fluoroquinolone-resistant Streptococcus pneumoniae after 7-valent conjugate vaccination, Spain.

Emerging infectious diseases - 1 Jun 2009

de la Campa Adela G, Ardanuy Carmen, Balsalobre Luz, Pérez-Trallero Emilio, Marimón Jose M, Fenoll Asunción, Liñares Josefina

Abstract excerpt

Among 4,215 Streptococcus pneumoniae isolates obtained in Spain during 2006, 98 (2.3%) were ciprofloxacin resistant (3.6% from adults and 0.14% from children). In comparison with findings from a 2002 study, global resistance remained stable. Low-level resistance (30 isolates with MIC 4-8 microg/mL) was caused by a reserpine-sensitive efflux phenotype (n = 4) or single topoisomerase IV (parC [n = 24] or parE [n =...

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Identifiers

PMID: 19523289
DOI: 10.3201/eid1506.080684
PMCID: PMC2727337

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