Article
Changes in fluoroquinolone-resistant Streptococcus pneumoniae after 7-valent conjugate vaccination, Spain.
Emerging infectious diseases - 1 Jun 2009
de la Campa Adela G, Ardanuy Carmen, Balsalobre Luz, Pérez-Trallero Emilio, Marimón Jose M, Fenoll Asunción, Liñares Josefina
Abstract excerpt
Among 4,215 Streptococcus pneumoniae isolates obtained in Spain during 2006, 98 (2.3%) were ciprofloxacin resistant (3.6% from adults and 0.14% from children). In comparison with findings from a 2002 study, global resistance remained stable. Low-level resistance (30 isolates with MIC 4-8 microg/mL) was caused by a reserpine-sensitive efflux phenotype (n = 4) or single topoisomerase IV (parC [n = 24] or parE [n =...
Topics
- Adult
- Anti-Bacterial Agents
- Bacterial Proteins
- Child
- Child, Preschool
- Ciprofloxacin
- Drug Resistance, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- Fluoroquinolones
- Genotype