Article
Genetic characterization of fluoroquinolone-resistant Streptococcus pneumoniae strains isolated during ciprofloxacin therapy from a patient with bronchiectasis.
Antimicrobial agents and chemotherapy - 1 Apr 2003
de la Campa Adela G, Ferrandiz María-José, Tubau Fe, Pallarés Román, Manresa Federico, Liñares Josefina
Abstract excerpt
Five Spain(9V-3) Streptococcus pneumoniae strains were isolated from a patient with bronchiectasis who had received long-term ciprofloxacin therapy. One ciprofloxacin-susceptible strain was isolated before treatment, and four ciprofloxacin-resistant strains were isolated during treatment. The resistant strains were derived from the susceptible strain either by a parC mutation (low-level resistance) or by parC and...
Topics
- Anti-Infective Agents
- Bronchiectasis
- Ciprofloxacin
- Drug Resistance, Bacterial
- Humans
- Male
- Middle Aged
- Mutation
- Streptococcus pneumoniae