Article
Genetic variants of hepatocyte nuclear factor-1beta in Chinese young-onset diabetic patients with nephropathy.
Journal of diabetes and its complications - 1 Jan 2000
So W Y, Ng Maggie C Y, Horikawa Yukio, Njølstad Pal R, Li June K Y, Ma Ronald C W, Bell Graeme I, Chan Juliana C N
Abstract excerpt
In Hong Kong, the prevalence of diabetes is estimated to be 2% in the young population. In the diabetic population, 30% of patients have diagnosis before the age of 40 years. Besides, 30% of young diabetic patients have varying degrees of albuminuria. Mutations in the gene encoding the hepatocyte nuclear factor (HNF)-1beta are associated with a subtype of maturity-onset diabetes of the young (MODY 5)...
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