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Identification of novel variants in the hepatocyte nuclear factor-1alpha gene in South Indian patients with maturity onset diabetes of young.

The Journal of clinical endocrinology and metabolism - 1 Jun 2009

Radha V, Ek J, Anuradha S, Hansen T, Pedersen O, Mohan V

Abstract excerpt

CONTEXT: Mutations in the HNF 1A gene are the most common cause of maturity-onset diabetes of the young (MODY) in most populations. India currently has the largest number of people with diabetes in the world, and onset of type 2 diabetes occurs at a younger age with possible overlap with MODY. There are very few data on MODY mutations from India. OBJECTIVE: The objective was to screen coding and promoter regions...

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Cells, Cultured
Diabetes Mellitus, Type 2
DNA Mutational Analysis
Family
Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatocyte Nuclear Factor 1-alpha

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PMID: 19336507
DOI: 10.1210/jc.2008-2371

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Identification of novel variants in the hepatocyte nuclear factor-1alpha gene in South Indian patients with maturity onset diabetes of young.PMID 19336507Read ↗

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HNF1A gene mutation (c.811del, p.Arg271Glyfs) causing maturity onset of diabetes of the young 3: a case study of an Indian patientSemantic proximity Read ↗

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