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Mutations in the coding regions of the hepatocyte nuclear factor 4 alpha in Iranian families with maturity onset diabetes of the young.

Cardiovascular diabetology - 10 Dec 2009

Taghavi Seyed Morteza, Fatemi Seyedeh Seddigheh, Rafatpanah Houshang, Ganjali Rashin, Tavakolafshari Jalil, Valizadeh Narges

Abstract excerpt

Hepatocyte nuclear factor 4alpha (HNF4alpha) is a nuclear receptor involved in glucose homeostasis and is required for normal beta cell function. Mutations in the HNF4alpha gene are associated with maturity onset diabetes of the young type 1 (MODY1). The aim of the present study was to determine the prevalence and nature of mutations in HNF4alpha gene in Iranian patients with a clinical diagnosis of MODY and...

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Age of Onset
Asian People
Blood Glucose
Diabetes Mellitus, Type 2
Glucose Tolerance Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatocyte Nuclear Factor 4

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PMID: 20003313
DOI: 10.1186/1475-2840-8-63
PMCID: PMC2797770

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Mutations in the coding regions of the hepatocyte nuclear factor 4 alpha in Iranian families with maturity onset diabetes of the young.PMID 20003313Read ↗

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