Article
[Involvement of the immunological system in the pathogenesis of transmissible spongiform encephalopathies].
Revista de neurologia - 1 Jan 2000
Brun A, Castilla J, Parra B, Rodríguez F, Torres J M
Abstract excerpt
OBJECTIVE: We review the current knowledge relative to the role of different immune system components and their contribution the spread of prions throughout the infected organism. DEVELOPMENT: During the last years research made on transmissible spongiform encephalopathies conducted to the assumption that changes in the structure of a determined protein (prion protein, PrP) may become self-propagative. The...
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