Article
Amyloidoses of the nervous system in the transmissible dementias.
Archives of medical research - 1 Jan 1992
Piccardo P
Abstract excerpt
The transmissible spongiform encephalopathies, both in humans and in animals, are neurodegenerative diseases which do not evoke an immune response in the host. The search for the etiological agent has led to the prion hypothesis, which proposes that a host-encoded protein may be the causal agent itself or a part of it. In humans, a low percentage of these transmissible encephalopathies are familial....
Topics
- Amyloidosis
- Animals
- Cricetinae
- Humans
- Mammals
- Mice
- Mutation
- PrPSc Proteins
- Prion Diseases
- Prions
- Species Specificity