Article
[Molecular basis of familial and sporadic forms of human prion diseases].
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine - 1 Jan 1994
Laplanche J L
Abstract excerpt
Prion diseases, also known as transmissible subacute spongiform encephalopathies (TSSE), are rare neurodegenerative disorders of both humans and animals. Their biochemical hallmark is an accumulation in the brain of an abnormal form of the host-encoded prion protein (PrP). This pathological accum...
Topics
- Aged
- Amyloid
- Codon
- Creutzfeldt-Jakob Syndrome
- Drug Contamination
- Female
- Genes
- Genetic Predisposition to Disease
- Genotype
- Growth Hormone
- Humans
- Iatrogenic Disease
- Male
- Middle Aged
- Nerve Tissue Proteins
- Point Mutation
- Polymorphism, Genetic
- Prion Diseases