Article
Prion diseases and the spleen.
Viral immunology - 1 Jan 2004
Daude Nathalie
Abstract excerpt
Transmissible spongiform encephalopathies are fatal neurodegenerative disorders that include Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy and scrapie in sheep and goats. Transmissible spongiform encephalopathies are thought by some to result from changes in the conformation of a membrane glycoprotein called PrPC (prion protein) into a pathogenic form, PrPSc, which constitutes the major...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
