Article
Altered lymphocyte homeostasis after oral prion infection in mouse.
Veterinary immunology and immunopathology - 15 Apr 2008
Segundo F Díaz-San, Sevilla N, Gutiérrez J P, Brun A
Abstract excerpt
Transmissible spongiform encephalopathies (TSEs) or prion diseases develop as central nervous system (CNS) disorders characterized by extremely long incubation periods. Although TSEs do not go along with inflammatory infiltrates and/or antibody production against the prion protein (PrP(Sc)), the immune system plays an important role in pathogenesis as long as different lymphoid organs (Peyer's patches, lymph...
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