Article
Analysis of genetic alterations, classified according to their DNA ploidy pattern, in the progression of colorectal adenomas and early colorectal carcinomas.
The Journal of pathology - 1 Jun 2003
Sugai Tamostu, Takahashi Hiroshi, Habano Wataru, Nakamura Shin-ichi, Sato Kimihiko, Orii Seishi, Suzuki Kazuyuki
Abstract excerpt
DNA aneuploidy is a biological marker of the oncogenic potential of colorectal adenomas. The accumulation of genetic alterations of cancer-related genes is also essential for colorectal carcinogenesis. However, it is unclear whether there is any relationship between these genetic alterations and the DNA ploidy of colon tumour cells in the progression of colorectal adenomas and early colorectal carcinomas. Here we...
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