Article
Familial Parkinson's disease: a hint to elucidate the mechanisms of nigral degeneration.
Journal of neurology - 1 Oct 2003
Hattori Nobutaka, Kobayashi Hirokazu, Sasaki-Hatano Yasuko, Sato Kenichi, Mizuno Yoshikuni
Abstract excerpt
In the majority of patients with Parkinson's disease (PD), it is now clear that genetic factors contribute to the pathogenesis of PD, although the contribution of genetic and environmental factors remains to be elucidated. The contribution of genetic factors to the pathogenesis of PD is supported by the demonstration of the high concordance in twins, increased risk among relatives of PD patients in case control...
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