Article
Role of Valpha 14 NKT cells in the development of impaired liver regeneration in vivo.
Hepatology (Baltimore, Md.) - 1 Nov 2003
Ito Hiroyasu, Ando Kazuki, Nakayama Toshinori, Taniguchi Masaru, Ezaki Takayuki, Saito Kuniaki, Takemura Masao, Sekikawa Kenji, Imawari Michio, Seishima Mitsuru, Moriwaki Hisataka
Abstract excerpt
Although we have previously demonstrated that IL-12 stimulation increases the number of hepatic natural killer (NK) T (NKT) cells and enhances liver injury during the early phase of liver regeneration, the role of NKT cells has remained unknown. We therefore evaluated the influence of NKT cells activated by IL-12 or by alpha-galactosylceramide (alpha-GalCer) on murine liver regeneration using Valpha 14 NKT...
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