Article
Changes of liver-resident NK cells during liver regeneration in rats.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 1995
Vujanovic N L, Polimeno L, Azzarone A, Francavilla A, Chambers W H, Starzl T E, Herberman R B, Whiteside T L
Abstract excerpt
To determine the role of NK cells in regulation of tissue growth, the phenotype and function of liver-resident NK cells were studied after 70% partial hepatectomy in rats. The process of liver regeneration was generally completed by day 14. In contrast, the number of liver-resident NK cells (NKR-P1bright) was restored as early as day 3 after partial hepatectomy. However, spontaneous functions of liver-resident NK...
Topics
- Animals
- Antibodies, Monoclonal
- Cytotoxicity, Immunologic
- Hepatectomy
- Immune Tolerance
- Killer Cells, Natural
- Liver
- Liver Regeneration
- Lymphocyte Depletion
- Male
- Phenotype
