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Article

Contribution of Toll‐like receptor/myeloid differentiation factor 88 signaling to murine liver regeneration†

19 Feb 2005

Abstract excerpt

Toll-like receptors (TLRs) act as innate immune signal sensors and play central roles in host defense. Myeloid differentiation factor (MyD) 88 is a common adaptor molecule required for signaling mediated by TLRs. When the receptors are activated, cells bearing TLRs produce various proinflammatory cytokines in a MyD88-dependent manner. Liver regeneration following partial hepatectomy (PH) requires innate immune...

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PMID: 15723296
DOI: 10.1002/hep.20603

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