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Article

Polymorphisms in DNA double-strand break repair genes and breast cancer risk in the Nurses' Health Study.

Carcinogenesis - 1 Feb 2004

Han Jiali, Hankinson Susan E, Ranu Hardeep, De Vivo Immaculata, Hunter David J

Abstract excerpt

Genetic polymorphisms in double-strand break repair genes may influence DNA repair capacity and, in turn, confer predisposition to breast cancer. We prospectively assessed the associations of candidate polymorphisms G31479A (R188H) in XRCC2, A4541G (5'-UTR), A17893G (IVS5-14) and C18067T (T241 M) in XRCC3, and C299T (5'-UTR) and T1977C (D501D) in Ligase IV with breast cancer risk in a nested case-control study...

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Identifiers

PMID: 14578164
DOI: 10.1093/carcin/bgh002

Genes

XRCC2
XRCC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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