Article
Cryptic splicing sites are differentially utilized in vivo.
The FEBS journal - 1 Mar 2008
Haj Khelil Amel, Deguillien Mireille, Morinière Madeleine, Ben Chibani Jemni, Baklouti Faouzi
Abstract excerpt
It has long been considered that cryptic splice sites are ignored by the splicing machinery in the context of intact genuine splice sites. In the present study, it is shown that cryptic splice sites are utilized in all circumstances, when the authentic site is intact, partially functional or completely abolished. Their use would therefore contribute to a background lack of fidelity in the context of the wild-type...
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