Article
Construction of a novel database containing aberrant splicing mutations of mammalian genes.
Gene - 20 Apr 1994
Nakai K, Sakamoto H
Abstract excerpt
To explore the rules for mammalian splice-site selection using a statistical approach, we constructed an aberrant splicing database containing an extensive collection of mammalian genetic disease mutations (90 genes, 209 mutations). From this database, we confirmed that: (1) more than 90% of muta...
Topics
- Consensus Sequence
- Databases, Factual
- Exons
- Humans
- Mutation
- Point Mutation
- RNA Splicing