Article
Immunohistochemistry and c-kit gene analysis in determining malignancy in gastrointestinal stromal tumors.
Hepato-gastroenterology - 1 Jan 2000
Yamaguchi Masahiko, Tate Genshu, Endo Yutaka, Miyaki Michiko
Abstract excerpt
BACKGROUND/AIMS: Usefulness of immunohistochemistry and c-kit proto-oncogene mutation was examined for determining malignancy in 24 cases of gastrointestinal stromal tumors. METHODOLOGY: Cases were histologically diagnosed and subjected to immunohistochemical staining and c-kit gene analysis. All parameters were compared to prognosis. RESULTS: There were significant differences in tumor size, central necrosis,...
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