Article
[Expression and mutation of c-kit gene in gastrointestinal stromal tumor].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Sept 2002
Ma Dalie, Liu Xiaohong, Cai Zailong, Xie Qiang
Abstract excerpt
OBJECTIVE: To investigate the effect of the expression and mutation of c-kit gene and its relationship with clinical pathology and prognosis of gastrointestinal stromal tumor (GIST). METHODS: Immunohistochemical and PCR-SSCP techniques were used to detect c-kit protein expression and c-kit gene exon 11 mutation in 82 patients with GIST. RESULTS: The positive c-kit protein expression and c-kit gene mutation rates...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.