[Effect of c-kit gene mutation on prognosis of gastrointestinal stromal tumor].

Abstract excerpt

OBJECTIVE: To evaluate the clinical signification of c-kit gene mutation in gastrointestinal stromal tumor (GIST) and examine whether the presence of mutation of c-kit gene is important as a prognostic factor. METHODS: The c-kit mutation had been detected by PCR-SSCP, DNA sequence, statistical comparison were used for the relationship of c-kit gene mutation and clinical pathology, clinical behavior, recurrence,...

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• Age Factors
• DNA Mutational Analysis
• Gastrointestinal Neoplasms
• Polymorphism, Single-Stranded Conformational
• Prognosis