Article
Polymorphisms in the CYP1A1 gene are associated with prostate cancer risk.
International journal of cancer - 1 Sept 2003
Chang Bao-li, Zheng Siqun L, Isaacs Sarah D, Turner Aubrey, Hawkins Gregory A, Wiley Kathy E, Bleecker Eugene R, Walsh Patrick C, Meyers Deborah A, Isaacs William B, Xu Jianfeng
Abstract excerpt
CYP1A1 is likely to play an important role in the etiology of CaP through its function in activating environmental procarcinogens and catalyzing the oxidative metabolites of estrogens. To test the hypothesis that genetic polymorphisms in the CYP1A1 gene may be associated with the risk for CaP, we...
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