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Article

Genetic variants of the CYP1B1 gene as predictors of biochemical recurrence after radical prostatectomy in localized prostate cancer patients.

Medicine - 1 Jul 2016

Gu Cheng-Yuan, Qin Xiao-Jian, Qu Yuan-Yuan, Zhu Yu, Wan Fang-Ning, Zhang Gui-Ming, Sun Li-Jiang, Zhu Yao, Ye Ding-Wei

Abstract excerpt

Clinically localized prostate cancer is curative. Nevertheless many patients suffered from biochemical recurrence (BCR) after radical prostatectomy (RP). Mounting evidence suggest that estrogen and xenobiotic carcinogens play an essential role in progression of prostate cancervia oxidative estrogen metabolism. CYP1B1 is an enzyme involved in the hydroxylation of estrogens, a reaction of key relevance in estrogen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27399092
DOI: 10.1097/MD.0000000000004066
PMCID: PMC5058821

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BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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