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Article

Forebrain-specific neuronal inhibition of nuclear factor-kappaB activity leads to loss of neuroprotection.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Oct 2003

Fridmacher Valérie, Kaltschmidt Barbara, Goudeau Bertrand, Ndiaye Delphine, Rossi Francesco Mattia, Pfeiffer Julia, Kaltschmidt Christian, Israël Alain, Mémet Sylvie

Abstract excerpt

The transcription factor Rel/nuclear factor (NF)-kappaB is known for its fundamental role in regulating immune and inflammatory responses. In the brain, constitutive NF-kappaB activity has been detected exclusively in neurons, and a large diversity of stimuli have been reported to induce NF-kappaB activity. Yet the function of this transcription factor in the nervous system remains unclear, and its role in...

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PMID: 14561868
PMCID: PMC6740573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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