Article
Conditional protein phosphorylation regulates BK channel activity in rat cerebellar Purkinje neurons.
The Journal of physiology - 15 Oct 2003
Widmer Hélène A, Rowe Iain C M, Shipston Michael J
Abstract excerpt
Large conductance calcium- and voltage-activated potassium (BK) channels are widely expressed in the mammalian central nervous system. Although the activity of BK channels in endocrine and vascular cells is regulated by protein kinases and phosphatases associated with the channel complex, direct evidence for such modulation in neurons is largely lacking. Single-channel analysis from inside-out patches isolated...
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